“New directions in science are launched by new tools much more often than by new concepts.” -Freeman J. Dyson

Over the past five years, there has been a revolution in the availability of human tissues and in the scientific techniques available for their study.

· Cutting-edge techniques are now available that allow imaging, protein expression and gene expression analyses on formalin fixed, paraffin embedded tissues, the most common way of preserving skin biopsies taken in the course of clinical care and for research studies.

· Sophisticated biobanks have been assembled that allow access to living, highly validated patients as well as banked, archived skin specimens, searchable by diagnoses.

· However, these sophisticated technologies and biobanks are only available in the largest academic medical centers and they require specialized support and reagents in order to use them successfully.

Objective of the Center: To enable access to cutting-edge biobanks and technologies to any researcher at any institution who wishes to carry out human skin disease research using human cells and tissues with the goal of accelerating human skin disease research. Additionally, the Center aims to support and mentor people of color and other underrepresented individuals in science and medicine.

Center Leadership

Rachael Clark, MD, PhD

Center Director

Department of Dermatology

Brigham and Women’s Hospital

Harvard Medical School

Thomas Kupper, MD

Associate Center Director

Chairman of Dermatology

Brigham and Women’s Hospital

Harvard Medical School


The Human Tissues Biobank Core

Jon Aster, MD, PhD

Director, Biobank Core

Department of Pathology

Brigham and Women’s Hospital

Harvard Medical School


Elizabeth Karlson, MD

Associate Director, Biobank Core

Department of Rheumatology

Brigham and Women’s Hospital

Harvard Medical School

The Single Cell and Immunoanalysis Core

James Lederer,  PhD

Director, Single Cell and Immunoanalysis Core

Department of Surgery

Brigham and Women’s Hospital

Harvard Medical School

Kevin Wei, MD, PhD

Associate Director,  Single Cell and Immunoanalysis Core

Department of Rheumatology

Brigham and Women’s Hospital

Harvard Medical School

The Next Generation Tissue Analysis and Imaging Core

Neal Lindeman, MD

Director, Next Generation Tissue Analysis and Imaging Core

Department of Pathology

Brigham and Women’s Hospital

Harvard Medical School


The Diversity Committee

Sotonye Imadojemu, MD 

Co-Leader, Diversity Committee

Department of Dermatology

Brigham and Women’s Hospital

Harvard Medical School

Deborah Scott, MD

Co-Leader, Diversity Committee

Department of Dermatology

Brigham and Women’s Hospital

Harvard Medical School

Interested in learning more?